The AXIOS™ Stent and Delivery System ("AXIOS System") enables endoscopic delivery of an anastomotic stent. The stent produces endoscopically what until now has only been possible through surgery. Creating an anastomotic conduit between two lumens enables blockages and strictures to be bypassed and large fluid collections to be drained.
The AXIOS System consists of two components: the catheter-based delivery system and an implantable stent. Under combined endoscopic and imaging guidance, the catheter is advanced, the stent deployed, and the catheter withdrawn. The stent has two large flanges to hold the tissue layers together and a large diameter for effective drainage. It is fully covered to prevent leakage and to enable removal. The stent creates a translumenal conduit between the wall of the gastrointestinal tract (e.g. stomach or duodenum) and a neighboring fluid-filled cavity (e.g. pancreatic pseudocyst, gallbladder, bile duct).
The AXIOS Stent design is intended to overcome the limitations of current options to facilitate drainage. Plastic double pigtail stents (the most widely-used stent for pseudocyst drainage) have small lumen diameters and may occlude and require replacement. Expandable metal stents have a large lumen; however the straight configuration makes them prone to migration. The stent ends may also cause tissue injury.